Table 2: Treatment patterns.
|
|
LoT1 |
LoT2 |
LoT3 |
LoT4 |
|
Prescribing specialist,* n (%) |
|
|
|
|
|
Primary care provider |
12,220,654 (71.6%) |
6,732,749 (69.2%) |
4,364,404 (69.1%) |
2,965,790 (67.7%) |
|
Primary care physician |
9,302,461 (54.5%) |
4,995,425 (51.4%) |
3,278,823 (51.9%) |
2,236,060 (51.1%) |
|
Nurse practitioner/ |
2,918,193 (17.1%) |
1,737,324 (17.9%) |
1,085,581 (17.2%) |
729,730 |
|
Cardiologist |
1,566,008 |
1,130,709 (11.6%) |
836,051 |
656,771 |
|
Nephrologist |
237,303 (1.4%) |
189,872 (2.0%) |
141,888 (2.2%) |
114,659 (2.6%) |
|
Endocrinologist |
87,208 (0.5%) |
47,264 (0.5%) |
30,778 (0.5%) |
21,296 (0.5%) |
|
Infectious disease specialist |
34,361 (0.2%) |
16,997 (0.2%) |
10,368 (0.2%) |
6,721 (0.2%) |
|
Other |
676,222 (4.0%) |
476,781 (4.9%) |
266,515 (4.2%) |
177,957 (4.1%) |
|
Specialist not specified |
2,255,940 (13.2%) |
1,129,657 (11.6%) |
667,764 |
435,769 |
|
Combination therapy with 2+ classes, n (%) |
8,012,319 (46.9%) |
5,254,610 (54.0%) |
3,620,098 (57.3%) |
2,504,016 (57.2%) |
|
Fixed-dose combination |
2,453,370 (14.4%) |
1,131,719 (11.6%) |
683,444 |
413,716 |
|
Free-dose combination |
5,558,949 (32.6%) |
4,122,891 (42.4%) |
2,936,654 (46.5%) |
2,090,300 (47.7%) |
|
Number of patients receiving guideline-recommended antihypertensive classes,† n (%) |
|
|
|
|
|
Using at least 1 of the classes |
13,519,507 (79.2%) |
7,299,206 (75.1%) |
4,743,062 (75.1%) |
3,183,325 (72.7%) |
|
Monotherapy using only the classes |
6,158,723 (36.1%) |
2,655,685 (27.3%) |
1,564,670 (24.8%) |
1,023,128 (23.4%) |
|
Combination therapy with 2+ classes using 2 of the 4 classes |
3,840,964 (47.9%) |
2,169,261 (41.3%) |
1,435,466 (39.7%) |
927,950 (37.1%) |
|
Combination therapy with 3+ classes using 3 of the 4 classes |
647,436 (24.3%) |
419,322 (21.4%) |
288,133 (20.2%) |
188,851 (18.6%) |
|
Combination therapy with 4+ classes using 3 of the 4 classes |
257,224 (40.3%) |
182,109 (34.7%) |
131,182 (33.4%) |
92,084 (31.7%) |
* Measured 30 days prior or on the start date of the anti-hypertensive medication class and provider assigned using a hierarchy of cardiologist, nephrologist, endocrinologist, primary care, nurse practitioner/physician assistant, other, unknown.
† Angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) plus dihydropyridine calcium channel blocker (DHP-CCB) and thiazide-like diuretic (thiazide)